Siquil
Brand names,
Siquil
Analogs
Siquil
Brand Names Mixture
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Chemical_Formula
C18H19F3N2S
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
352.418 g/mol
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Melting Point
No information avaliable
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H2O Solubility
No information avaliable
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State
Solid
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LogP
5.888
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Dosage Forms
Solution for intramuscular injection
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Indication
Used mainly in the management of psychoses. Also used to control nausea and vomiting.
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Pharmacology
Triflupromazine is a member of a class of drugs called phenthiazines, which are dopamine D1/D2 receptor antagonists. Phenothiazines are used to treat serious mental and emotional disorders, including schizophrenia and other psychotic disorders. It reduces anxiety, emotional withdrawal, hallucinations, disorganized thoughts, blunted mood, and suspiciousness. Triflupromazine is used particularly to control violent behavior during acute episodes of psychotic disorders. It can also be used to control severe nausea and vomiting, severe hiccups, and moderate to severe pain in some hospitalized patients. Triflupromazine acts on the central nervous system.
Siquil
Absorption
Absorption may be erratic and peak plasma concentrations show large interindividual differences.
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side effects and Toxicity
Symptoms of overdose include agitation, coma, convulsions, difficulty breathing, difficulty swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, and restlessness.
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals