Adazine
Brand names,
Adazine
Analogs
Adazine
Brand Names Mixture
Adazine
Chemical_Formula
C18H19F3N2S
Adazine
RX_link
No information avaliable
Adazine
fda sheet
Adazine
msds (material safety sheet)
Adazine
Synthesis Reference
No information avaliable
Adazine
Molecular Weight
352.418 g/mol
Adazine
Melting Point
No information avaliable
Adazine
H2O Solubility
No information avaliable
Adazine
State
Solid
Adazine
LogP
5.888
Adazine
Dosage Forms
Solution for intramuscular injection
Adazine
Indication
Used mainly in the management of psychoses. Also used to control nausea and vomiting.
Adazine
Pharmacology
Triflupromazine is a member of a class of drugs called phenthiazines, which are dopamine D1/D2 receptor antagonists. Phenothiazines are used to treat serious mental and emotional disorders, including schizophrenia and other psychotic disorders. It reduces anxiety, emotional withdrawal, hallucinations, disorganized thoughts, blunted mood, and suspiciousness. Triflupromazine is used particularly to control violent behavior during acute episodes of psychotic disorders. It can also be used to control severe nausea and vomiting, severe hiccups, and moderate to severe pain in some hospitalized patients. Triflupromazine acts on the central nervous system.
Adazine
Absorption
Absorption may be erratic and peak plasma concentrations show large interindividual differences.
Adazine
side effects and Toxicity
Symptoms of overdose include agitation, coma, convulsions, difficulty breathing, difficulty swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, and restlessness.
Adazine
Patient Information
No information avaliable
Adazine
Organisms Affected
Humans and other mammals