Rocuronium bromide en es it fr

Rocuronium bromide Brand names, Rocuronium bromide Analogs

Rocuronium bromide Brand Names Mixture

  • No information avaliable

Rocuronium bromide Chemical_Formula


Rocuronium bromide RX_link

Rocuronium bromide fda sheet

Rocuronium_bromide FDA

Rocuronium bromide msds (material safety sheet)

Rocuronium_bromide MSDS

Rocuronium bromide Synthesis Reference

No information avaliable

Rocuronium bromide Molecular Weight

416.574 g/mol

Rocuronium bromide Melting Point

134.5 oC

Rocuronium bromide H2O Solubility

Practically insoluble (22 mg/L)

Rocuronium bromide State


Rocuronium bromide LogP


Rocuronium bromide Dosage Forms

Oral tablets (25 mg, 50 mg, or 100 mg)

Rocuronium bromide Indication

Used primarily to treat low-renin hypertension, hypokalemia, and Conn's syndrome.

Rocuronium bromide Pharmacology

Spironolactone is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics. On its own, spironolactone is only a weak diuretic, but it can be combined with other diuretics. Due to its anti-androgen effect, it can also be used to treat hirsutism, and is a common component in hormone therapy for male-to-female transgendered people. Spironolactone inhibits the effect of aldosterone by competing for intracellular aldosterone receptor in the distal tubule cells. This increases the secretion of water and sodium, while decreasing the excretion of potassium. Spironolactone has a fairly slow onset of action, taking several days to develop and similarly the effect diminishes slowly.

Rocuronium bromide Absorption

Fairly rapidly absorbed from the gastrointestinal tract. Food increases the bioavailability of unmetabolized spironolactone by almost 100%.

Rocuronium bromide side effects and Toxicity

The oral LD50 of spironolactone is greater than 1,000 mg/kg in mice, rats, and rabbits. Acute overdosage of spironolactone may be manifested by drowsiness, mental confusion, maculopapular or erythematous rash, nausea, vomiting, dizziness, or diarrhea. Spironolactone has been shown to be a tumorigen in chronic toxicity studies in rats.

Rocuronium bromide Patient Information

Rocuronium bromide Organisms Affected

Humans and other mammals