Procethazine en es it fr

Procethazine Brand names, Procethazine Analogs

Procethazine Brand Names Mixture

  • No information avaliable

Procethazine Chemical_Formula

No information avaliable

Procethazine RX_link

Procethazine fda sheet

Procethazine FDA

Procethazine msds (material safety sheet)

Procethazine Synthesis Reference

No information avaliable

Procethazine Molecular Weight

618.248 g/mol

Procethazine Melting Point

No information avaliable

Procethazine H2O Solubility


Procethazine State


Procethazine LogP

No information avaliable

Procethazine Dosage Forms

Tablets (off-white, film-coated, solid tablets containing 625 mg colesevelam)

Procethazine Indication

For use, alone or in combination with an HMG-CoA reductase inhibitor, as adjunctive therapy to diet and exercise for the reduction of elevated LDL cholesterol in patients with primary hypercholesterolemia (Fredrickson Type IIa).

Procethazine Pharmacology

Colesevelam is a high capacity bile-acid binding molecule. Colesevelam binds to bile acids in the intestine which reduces the amount of bile acids that are returned to the liver via enterohepatic circulation. Clinical studies have demonstrated that elevated levels of total cholesterol (total-C), LDL-C, and apolipoprotein B (Apo B, a protein associated with LDL-C) are associated with an increased risk of atherosclerosis in humans. Similarly, decreased levels of high-density lipoprotein cholesterol (HDL-C) are associated with the development of atherosclerosis. Epidemiological investigations have established that cardiovascular morbidity and mortality vary directly with the levels of total-C and LDL-C, and inversely with the level of HDL-C. The combination of colesevelam and an HMG-CoA reductase inhibitor is effective in further lowering serum total-C and LDL-C levels beyond that achieved by either agent alone.

Procethazine Absorption

Not hydrolyzed by digestive enzymes and is not absorbed.

Procethazine side effects and Toxicity

Symptoms of overdose may include eye irritation, constipation, abdominal cramps, nausea, vomiting, diarrhea, and hypersensitivity. However, as colesevelam is not absorbed, the risk of systemic toxicity is low. Doses in excess of 4.5 g per day have not been tested.

Procethazine Patient Information

Procethazine Organisms Affected

Humans and other mammals