Procef
Procef Brand names, Procef Analogs
Procef Brand Names Mixture
- No information avaliable
Procef Chemical_Formula
C18H19N3O5S
Procef RX_link
http://www.rxlist.com/cgi/generic/cefprozi.htm
Procef fda sheet
Procef msds (material safety sheet)
Procef Synthesis Reference
H. Hoshi et al., U.S. Pat. 4,520,022 (1985)
Procef Molecular Weight
389.427 g/mol
Procef Melting Point
218-225oC
Procef H2O Solubility
55 mg/L
Procef State
Solid
Procef LogP
0.209
Procef Dosage Forms
Cefzil tablets contain cefprozil equivalent to 250 mg or 500 mg of anhydrous cefprozil.
Procef Indication
For the treatment of the following infections (respiratory, skin, soft tissue, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staph
Procef Pharmacology
Cefprozil, a semisynthetic, second-generation cephalosporin, is used to treat otitis media, soft-tissue infections, and respiratory tract infections.
Procef Absorption
Oral~95%
Procef side effects and Toxicity
Single 5000 mg/kg oral doses of cefprozil caused no mortality or signs of toxicity in adult, weaning or neonatal rats, or adult mice. A single oral dose of 3000 mg/kg caused diarrhea and loss of appetite in cynomolgus monkeys, but no mortality.
Procef Patient Information
Cefprozil is an antibiotic use to treat infections such as tonsillitis, ear infections, bronchitis, pneumonia or skin infections. This drug should not be used by those with allergies to the cephalosporin antibiotics. You should also consult with your pharmacist or physician if you are allergic to penicillin before taking this medication. This medication contains phenylalanine; caution is warranted for phenylketonuric patients. This medication has been known to falsely wshow glucose (sugar) in the urine. The most common side effects include nausea, vomiting and diarrhea. This medication should be taken for the full period prescribed. Even if you feel better after a day or two of medication, the full prescription should be taken to fully cure the infection.
Procef Organisms Affected
Enteric bacteria and other eubacteria
