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Podophyllotoxin Brand names, Podophyllotoxin Analogs

Podophyllotoxin Brand Names Mixture

  • No information avaliable

Podophyllotoxin Chemical_Formula

C8H17NO2

Podophyllotoxin RX_link

http://www.rxlist.com/cgi/generic4/lyrica.htm

Podophyllotoxin fda sheet

Podophyllotoxin msds (material safety sheet)

Podophyllotoxin Synthesis Reference

No information avaliable

Podophyllotoxin Molecular Weight

159.226 g/mol

Podophyllotoxin Melting Point

No information avaliable

Podophyllotoxin H2O Solubility

No information avaliable

Podophyllotoxin State

Solid

Podophyllotoxin LogP

0.844

Podophyllotoxin Dosage Forms

Capsule

Podophyllotoxin Indication

For management of neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia.

Podophyllotoxin Pharmacology

Pregabalin is a new anticonvulsant drug indicated as an add on therapy for partial onset seizures and for certain types of neuropathic pain. It was designed as a more potent successor to a related drug, gabapentin. Pregabalin binds to the alpha2-delta subunit of the voltage-gated calcium channel in the central nervous system. While pregabalin is a structural derivative of the inhibitory neurotransmitter gamma- aminobutyric acid (GABA), it does not bind directly to GABAA, GABAB, or benzodiazepine receptors, does not augment GABAA responses in cultured neurons, does not alter rat brain GABA concentration or have acute effects on GABA uptake or degradation. However, in cultured neurons prolonged application of pregabalin increases the density of GABA transporter protein and increases the rate of functional GABA transport. Pregabalin does not block sodium channels, is not active at opiate receptors, and does not alter cyclooxygenase enzyme activity. It is inactive at serotonin and dopamine receptors and does not inhibit dopamine, serotonin, or noradrenaline reuptake.

Podophyllotoxin Absorption

Well absorbed after oral administration.

Podophyllotoxin side effects and Toxicity

No information avaliable

Podophyllotoxin Patient Information

No information avaliable

Podophyllotoxin Organisms Affected

Humans and other mammals