Pipobroman
Brand names,
Pipobroman
Analogs
Pipobroman
Brand Names Mixture
Pipobroman
Chemical_Formula
C10H16Br2N2O2
Pipobroman
RX_link
No information avaliable
Pipobroman
fda sheet
Pipobroman
msds (material safety sheet)
Pipobroman
Synthesis Reference
No information avaliable
Pipobroman
Molecular Weight
356.054 g/mol
Pipobroman
Melting Point
> 300 oC
Pipobroman
H2O Solubility
2490 mg/L
Pipobroman
State
Solid
Pipobroman
LogP
0.256
Pipobroman
Dosage Forms
Tablet (25 mg)
Pipobroman
Indication
For the treatment of polycythaemia vera and refractory chronic myeloid leukaemia.
Pipobroman
Pharmacology
Pipobroman is an antineoplastic agent. Specifically it is a piperazine derivative with a chemical structure close to that of many DNA alkylating agents. Pipobroman has well documented clinical activity against polycythemia vera and essential thrombocythemia.
Pipobroman
Absorption
Well absorbed from the GI tract.
Pipobroman
side effects and Toxicity
Symptoms of overdose include hematologic toxicity, especially with chronic overdosage.
Pipobroman
Patient Information
No information avaliable
Pipobroman
Organisms Affected
Humans and other mammals