Amedel
Brand names,
Amedel
Analogs
Amedel
Brand Names Mixture
Amedel
Chemical_Formula
C10H16Br2N2O2
Amedel
RX_link
No information avaliable
Amedel
fda sheet
Amedel
msds (material safety sheet)
Amedel
Synthesis Reference
No information avaliable
Amedel
Molecular Weight
356.054 g/mol
Amedel
Melting Point
> 300 oC
Amedel
H2O Solubility
2490 mg/L
Amedel
State
Solid
Amedel
LogP
0.256
Amedel
Dosage Forms
Tablet (25 mg)
Amedel
Indication
For the treatment of polycythaemia vera and refractory chronic myeloid leukaemia.
Amedel
Pharmacology
Pipobroman is an antineoplastic agent. Specifically it is a piperazine derivative with a chemical structure close to that of many DNA alkylating agents. Pipobroman has well documented clinical activity against polycythemia vera and essential thrombocythemia.
Amedel
Absorption
Well absorbed from the GI tract.
Amedel
side effects and Toxicity
Symptoms of overdose include hematologic toxicity, especially with chronic overdosage.
Amedel
Patient Information
No information avaliable
Amedel
Organisms Affected
Humans and other mammals