Permax en es it fr

Permax Brand names, Permax Analogs

Permax Brand Names Mixture

  • No information avaliable

Permax Chemical_Formula


Permax RX_link

Permax fda sheet

Permax FDA

Permax msds (material safety sheet)

Permax MSDS

Permax Synthesis Reference

No information avaliable

Permax Molecular Weight

314.489 g/mol

Permax Melting Point

207.5 oC

Permax H2O Solubility

No information avaliable

Permax State


Permax LogP


Permax Dosage Forms


Permax Indication

Indicated as adjunctive treatment to levodopa/carbidopa in the management of the signs and symptoms of Parkinson’s disease.

Permax Pharmacology

Pergolide is an ergot derivative dopamine receptor agonist at both D1 and D2 receptor sites. Pergolide is 10 to 1,000 times more potent than bromocriptine on a milligram per milligram basis in various in vitro and in vivo test systems. Pergolide mesylate inhibits the secretion of prolactin in humans; it causes a transient rise in serum concentrations of growth hormone and a decrease in serum concentrations of luteinizing hormone. In Parkinson’s disease, pergolide mesylate is believed to exert its therapeutic effect by directly stimulating postsynaptic dopamine receptors in the nigrostriatal system.

Permax Absorption

Significant amount may be absorbed (evidence on bioavailability still lacking).

Permax side effects and Toxicity

Oral, rat LD50: 15 mg/kg. Symptoms of overdose include nausea, vomiting, convulsions, decreased blood pressure, and CNS stimulation.

Permax Patient Information

Permax Organisms Affected

Humans and other mammals