Paraplatin
Paraplatin Brand names, Paraplatin Analogs
Paraplatin Brand Names Mixture
- No information avaliable
Paraplatin Chemical_Formula
C6H12N2O4Pt2
Paraplatin RX_link
http://www.rxlist.com/cgi/generic3/carboplat.htm
Paraplatin fda sheet
Paraplatin msds (material safety sheet)
Paraplatin Synthesis Reference
No information avaliable
Paraplatin Molecular Weight
371.249 g/mol
Paraplatin Melting Point
No information avaliable
Paraplatin H2O Solubility
No information avaliable
Paraplatin State
Solid
Paraplatin LogP
No information avaliable
Paraplatin Dosage Forms
Solution
Paraplatin Indication
For the initial treatment of advanced ovarian carcinoma in established combination with other approved chemotherapeutic agents. One established combination regimen consists of PARAPLATIN and cyclophosphamide.
Paraplatin Pharmacology
Carboplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.
Paraplatin Absorption
No information avaliable
Paraplatin side effects and Toxicity
Toxic by ingestion. May be create toxic effect through inhalation or skin contact. May cause reproductive defects. May act as a sensitizer.
Paraplatin Patient Information
No information avaliable
Paraplatin Organisms Affected
Humans and other mammals
