Palifermin
Brand names,
Palifermin
Analogs
Palifermin
Brand Names Mixture
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Chemical_Formula
C721H1142N202O204S9
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
16192.7
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Melting Point
No information avaliable
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H2O Solubility
No information avaliable
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State
Liquid
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LogP
-0.650
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Dosage Forms
Solution (IV Injection)
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Indication
For treatment of mucositis (mouth sores)
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Pharmacology
Used in the prevention or treatment of oral mucoscitis (mouth ulcers arising from chemotherapy), Kepivance binds to the human keratinocyte growth factor (KGF) receptor on buccal cell surfaces. Kepivance acts as both a cell growth and survival factor by stimulating epithelial cell proliferation, differentiation, and migration around the tongue and mouth. The KGF receptor is found on many tissues particularly around the tongue, esophagus, salivary gland and other gastro-intestinal tract organs.
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Absorption
No information avaliable
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals