Kepivance (Amgen Inc)
Brand names,
Kepivance (Amgen Inc)
Analogs
Kepivance (Amgen Inc)
Brand Names Mixture
Kepivance (Amgen Inc)
Chemical_Formula
C721H1142N202O204S9
Kepivance (Amgen Inc)
RX_link
No information avaliable
Kepivance (Amgen Inc)
fda sheet
Kepivance (Amgen Inc)
msds (material safety sheet)
Kepivance (Amgen Inc)
Synthesis Reference
No information avaliable
Kepivance (Amgen Inc)
Molecular Weight
16192.7
Kepivance (Amgen Inc)
Melting Point
No information avaliable
Kepivance (Amgen Inc)
H2O Solubility
No information avaliable
Kepivance (Amgen Inc)
State
Liquid
Kepivance (Amgen Inc)
LogP
-0.650
Kepivance (Amgen Inc)
Dosage Forms
Solution (IV Injection)
Kepivance (Amgen Inc)
Indication
For treatment of mucositis (mouth sores)
Kepivance (Amgen Inc)
Pharmacology
Used in the prevention or treatment of oral mucoscitis (mouth ulcers arising from chemotherapy), Kepivance binds to the human keratinocyte growth factor (KGF) receptor on buccal cell surfaces. Kepivance acts as both a cell growth and survival factor by stimulating epithelial cell proliferation, differentiation, and migration around the tongue and mouth. The KGF receptor is found on many tissues particularly around the tongue, esophagus, salivary gland and other gastro-intestinal tract organs.
Kepivance (Amgen Inc)
Absorption
No information avaliable
Kepivance (Amgen Inc)
side effects and Toxicity
No information avaliable
Kepivance (Amgen Inc)
Patient Information
No information avaliable
Kepivance (Amgen Inc)
Organisms Affected
Humans and other mammals