PE2
PE2 Brand names, PE2 Analogs
PE2 Brand Names Mixture
- No information avaliable
PE2 Chemical_Formula
C10H15N5O3
PE2 RX_link
http://www.rxlist.com/cgi/generic3/penciclovir.htm
PE2 fda sheet
PE2 msds (material safety sheet)
PE2 Synthesis Reference
R. L. Jarvest, M. R. Harnden, U.S. pat. . 5,075,445 (1991)
PE2 Molecular Weight
253.258 g/mol
PE2 Melting Point
275-277 oC
PE2 H2O Solubility
1.7mg/ml
PE2 State
Solid
PE2 LogP
-1.62
PE2 Dosage Forms
Topical cream
PE2 Indication
Used to treat recurrent cold sores on the lips and face.
PE2 Pharmacology
Penciclovir is the active metabolite of the oral product famciclovir. The more favorable results observed with topical penciclovir versus topical acyclovir for the treatment of herpes labialis may be due to the longer intracellular half-life of penciclovir in HSV-infected cells.
PE2 Absorption
Measurable penciclovir concentrations were not detected in plasma or urine of healthy male volunteers (n= 12) following single or repeat application of the 1% cream at a dose of 180 mg penciclovir daily.
PE2 side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
PE2 Patient Information
PATIENT INFORMATION
Penciclovir
About Penciclovir
This belongs to the group of medicines known as antivirals.
It is used to treat infections caused by the Herpes simplex virus, such as cold sores.
Penciclovir is available in cream form.
It is also sometimes known as: Vectavir. You may notice the use of any of these names on the packaging of your medicine.
Before using Penciclovir
Before using any penciclovir cream make sure your doctor or pharmacist knows:
if you have ever had an allergic reaction to this or any other medicine
if you are using any other preparations, including those available to buy without a prescription, herbal and complementary
medicines
How to use Penciclovir
Use penciclovir cream exactly as directed by your doctor.
Always read the manufacturer's information leaflet, if possible, before beginning treatment.
Apply penciclovir cream every two hours while you are awake, for four days, unless otherwise directed by your doctor.
This medicine is for you. Never give it to others, even if their condition appears to be the same as yours.
Getting the most from your treatment
Penciclovir cream is best used as soon as possible after the symptoms of an infection begin (e.g. pain, burning or blisters).
Always wash and dry your hands thoroughly before and after handling penciclovir cream.
Complete the prescribed course of treatment with penciclovir, otherwise your infection is likely to recur. Treatment with
penciclovir cream usually lasts four days.
Before using any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to use alongside
penciclovir cream.
You should see an improvement in your condition after a few days. If your condition does not seem to be getting better after
four days, consult your doctor for advice.
Can Penciclovir cause problems?
Penciclovir cream occasionally causes skin irritation such as stinging, burning and numbness. This should soon disappear. If
it doesn't or if it becomes severe, stop using penciclovir and ask your doctor or pharmacist for advice.
If you experience any other worrying symptoms, which you think may be due to this preparation, consult your doctor or
pharmacist.
How to store Penciclovir
Keep out of reach of children.
Store in a cool, dry place, away from direct light and heat.
Never keep out of date or unwanted medicines. Discard them safely out of the reach of children or take them to your local
pharmacist who will dispose of unwanted medicines for you.
Penciclovir
About Penciclovir
This belongs to the group of medicines known as antivirals.
It is used to treat infections caused by the Herpes simplex virus, such as cold sores.
Penciclovir is available in cream form.
It is also sometimes known as: Vectavir. You may notice the use of any of these names on the packaging of your medicine.
Before using Penciclovir
Before using any penciclovir cream make sure your doctor or pharmacist knows:
if you have ever had an allergic reaction to this or any other medicine
if you are using any other preparations, including those available to buy without a prescription, herbal and complementary
medicines
How to use Penciclovir
Use penciclovir cream exactly as directed by your doctor.
Always read the manufacturer's information leaflet, if possible, before beginning treatment.
Apply penciclovir cream every two hours while you are awake, for four days, unless otherwise directed by your doctor.
This medicine is for you. Never give it to others, even if their condition appears to be the same as yours.
Getting the most from your treatment
Penciclovir cream is best used as soon as possible after the symptoms of an infection begin (e.g. pain, burning or blisters).
Always wash and dry your hands thoroughly before and after handling penciclovir cream.
Complete the prescribed course of treatment with penciclovir, otherwise your infection is likely to recur. Treatment with
penciclovir cream usually lasts four days.
Before using any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to use alongside
penciclovir cream.
You should see an improvement in your condition after a few days. If your condition does not seem to be getting better after
four days, consult your doctor for advice.
Can Penciclovir cause problems?
Penciclovir cream occasionally causes skin irritation such as stinging, burning and numbness. This should soon disappear. If
it doesn't or if it becomes severe, stop using penciclovir and ask your doctor or pharmacist for advice.
If you experience any other worrying symptoms, which you think may be due to this preparation, consult your doctor or
pharmacist.
How to store Penciclovir
Keep out of reach of children.
Store in a cool, dry place, away from direct light and heat.
Never keep out of date or unwanted medicines. Discard them safely out of the reach of children or take them to your local
pharmacist who will dispose of unwanted medicines for you.
PE2 Organisms Affected
Herpes simplex virus
