Oxcarbazepine
Oxcarbazepine Brand names, Oxcarbazepine Analogs
Oxcarbazepine Brand Names Mixture
- No information avaliable
Oxcarbazepine Chemical_Formula
C15H12N2O2
Oxcarbazepine RX_link
http://www.rxlist.com/cgi/generic3/oxcarbazepine.htm
Oxcarbazepine fda sheet
Oxcarbazepine msds (material safety sheet)
Oxcarbazepine Synthesis Reference
No information avaliable
Oxcarbazepine Molecular Weight
252.268 g/mol
Oxcarbazepine Melting Point
215.5 oC
Oxcarbazepine H2O Solubility
308 mg/L at 25 oC (SRC PhysProp estimated -- MEYLAN,WM et al. (1996))
Oxcarbazepine State
Solid
Oxcarbazepine LogP
1.807
Oxcarbazepine Dosage Forms
Suspension; Tablet (150 mg, 300 mg and 600 mg film coated)
Oxcarbazepine Indication
For use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults with epilepsy and as adjunctive therapy in the treatment of partial seizures in children ages 4-16 with epilepsy.
Oxcarbazepine Pharmacology
Oxcarbazepine is structurally a derivative of carbamazepine, adding an extra oxygen atom to the benzylcarboxamide group. This difference helps reduce the impact on the liver of metabolizing the drug, and also prevents the serious forms of anemia occasionally associated with carbamazepine. Aside from this reduction in side effects, it is thought to have the same mechanism as carbamazepine - sodium channel inhibition - and is generally used to treat the same conditions.
Oxcarbazepine Absorption
Completely absorbed following oral administration. Food has no effect on the rate and extent of absorption of oxcarbazepine.
Oxcarbazepine side effects and Toxicity
Isolated cases of overdose with oxcarbazepine have been reported. The maximum dose taken was approximately 24,000 mg. All patients recovered with symptomatic treatment.
Oxcarbazepine Patient Information
Oxcarbazepine Organisms Affected
Humans and other mammals
