PharmacyCodes



Orthoclone OKT3 (Ortho Biotech) en es it fr

Orthoclone OKT3 (Ortho Biotech) Brand names, Orthoclone OKT3 (Ortho Biotech) Analogs

Orthoclone OKT3 (Ortho Biotech) Brand Names Mixture

  • No information avaliable

Orthoclone OKT3 (Ortho Biotech) Chemical_Formula

C6460H9946N1720O2043S56

Orthoclone OKT3 (Ortho Biotech) RX_link

No information avaliable

Orthoclone OKT3 (Ortho Biotech) fda sheet

Orthoclone OKT3 (Ortho Biotech) msds (material safety sheet)

Orthoclone OKT3 (Ortho Biotech) Synthesis Reference

No information avaliable

Orthoclone OKT3 (Ortho Biotech) Molecular Weight

146189.7

Orthoclone OKT3 (Ortho Biotech) Melting Point

61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).

Orthoclone OKT3 (Ortho Biotech) H2O Solubility

No information avaliable

Orthoclone OKT3 (Ortho Biotech) State

Liquid

Orthoclone OKT3 (Ortho Biotech) LogP

-0.513

Orthoclone OKT3 (Ortho Biotech) Dosage Forms

Solution (IV injection)

Orthoclone OKT3 (Ortho Biotech) Indication

For treatment of organ transplant recipients, prevention of organ rejection

Orthoclone OKT3 (Ortho Biotech) Pharmacology

Used in organ transplant prophylaxis, Muromonab or OKT-3 binds specifically to the CD-3 complex, which is involved in antigen recognition and cell stimulation, on the surface of T lymphocytes. Immediately after administration CD-3-positive T lymphocytes are abruptly removed from circulation. It has been effective in reversing corticosteroid-resistant acute rejection in renal, liver, and cardiac transplant recipients.

Orthoclone OKT3 (Ortho Biotech) Absorption

No information avaliable

Orthoclone OKT3 (Ortho Biotech) side effects and Toxicity

No information avaliable

Orthoclone OKT3 (Ortho Biotech) Patient Information

No information avaliable

Orthoclone OKT3 (Ortho Biotech) Organisms Affected

Humans and other mammals