AntiCD3
AntiCD3 Brand names, AntiCD3 Analogs
AntiCD3 Brand Names Mixture
- No information avaliable
AntiCD3 Chemical_Formula
C6460H9946N1720O2043S56
AntiCD3 RX_link
No information avaliable
AntiCD3 fda sheet
AntiCD3 msds (material safety sheet)
AntiCD3 Synthesis Reference
No information avaliable
AntiCD3 Molecular Weight
146189.7
AntiCD3 Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
AntiCD3 H2O Solubility
No information avaliable
AntiCD3 State
Liquid
AntiCD3 LogP
-0.513
AntiCD3 Dosage Forms
Solution (IV injection)
AntiCD3 Indication
For treatment of organ transplant recipients, prevention of organ rejection
AntiCD3 Pharmacology
Used in organ transplant prophylaxis, Muromonab or OKT-3 binds specifically to the CD-3 complex, which is involved in antigen recognition and cell stimulation, on the surface of T lymphocytes. Immediately after administration CD-3-positive T lymphocytes are abruptly removed from circulation. It has been effective in reversing corticosteroid-resistant acute rejection in renal, liver, and cardiac transplant recipients.
AntiCD3 Absorption
No information avaliable
AntiCD3 side effects and Toxicity
No information avaliable
AntiCD3 Patient Information
No information avaliable
AntiCD3 Organisms Affected
Humans and other mammals
