Olmetec
Brand names,
Olmetec
Analogs
Olmetec
Brand Names Mixture
Olmetec
Chemical_Formula
C29H30N6O6
Olmetec
RX_link
http://www.rxlist.com/cgi/generic/benicar.htm
Olmetec
fda sheet
Olmetec
msds (material safety sheet)
Olmetec
Synthesis Reference
No information avaliable
Olmetec
Molecular Weight
558.585 g/mol
Olmetec
Melting Point
175-180 oC
Olmetec
H2O Solubility
No information avaliable
Olmetec
State
Solid
Olmetec
LogP
5.202
Olmetec
Dosage Forms
Tablet
Olmetec
Indication
For the treatment of hypertension
Olmetec
Pharmacology
Olmesartan Medoxomil, a specific angiotensin II type 1 antagonist, is used alone or with other antihypertensive agents to treat hypertension. Unlike the angiotensin receptor antagonist losartan, olmesartan does not have an active metabolite or possess uricosuric effects. Blockade of the angiotensin II receptor inhibits the negative regulatory feedback of angiotensin II on renin secretion, but the resulting increased plasma renin activity and circulating angiotensin II levels do not overcome the effect of olmesartan on blood pressure.
Olmetec
Absorption
Bioavailability is about 26%. Food does not affect the bioavailability of olmesartan.
Olmetec
side effects and Toxicity
Symptoms of overdose include dehydration (dry mouth, excessive thirst, muscle pain or cramps, nausea and vomiting, weakness), dizziness, low blood pressure, and slow or irregular heartbeat.
Olmetec
Patient Information
Olmetec
Organisms Affected
Humans and other mammals