Nimotop
Nimotop Brand names, Nimotop Analogs
Nimotop Brand Names Mixture
- No information avaliable
Nimotop Chemical_Formula
C21H26N2O7
Nimotop RX_link
http://www.rxlist.com/cgi/generic2/nimodip.htm
Nimotop fda sheet
Nimotop msds (material safety sheet)
Nimotop Synthesis Reference
No information avaliable
Nimotop Molecular Weight
418.44 g/mol
Nimotop Melting Point
No information avaliable
Nimotop H2O Solubility
No information avaliable
Nimotop State
Solid
Nimotop LogP
3.152
Nimotop Dosage Forms
Capsules
Nimotop Indication
For the treatment of subarachnoid bleeding.
Nimotop Pharmacology
Nimodipine belongs to the class of pharmacological agents known as calcium channel blockers. Nimodipine is indicated for the improvement of neurological outcome by reducing the incidence and severity of ischemic deficits in patients with subarachnoid hemorrhage from ruptured congenital aneurysms who are in good neurological condition post-ictus (e.g., Hunt and Hess Grades I-III). The contractile processes of smooth muscle cells are dependent upon calcium ions, which enter these cells during depolarization as slow ionic transmembrane currents. Nimodipine inhibits calcium ion transfer into these cells and thus inhibits contractions of vascular smooth muscle. In animal experiments, nimodipine had a greater effect on cerebral arteries than on arteries elsewhere in the body perhaps because it is highly lipophilic, allowing it to cross the blood brain barrier.
Nimotop Absorption
No information avaliable
Nimotop side effects and Toxicity
No information avaliable
Nimotop Patient Information
No information avaliable
Nimotop Organisms Affected
Humans and other mammals
