Nalfon
Brand names,
Nalfon
Analogs
Nalfon
Brand Names Mixture
Nalfon
Chemical_Formula
C24H33N3O4
Nalfon
RX_link
No information avaliable
Nalfon
fda sheet
Nalfon
msds (material safety sheet)
Nalfon
Synthesis Reference
No information avaliable
Nalfon
Molecular Weight
427.537 g/mol
Nalfon
Melting Point
No information avaliable
Nalfon
H2O Solubility
Very slightly soluble
Nalfon
State
Solid
Nalfon
LogP
1.876
Nalfon
Dosage Forms
Tablets (extended release - 500 mg)
Nalfon
Indication
For the treatment of chronic angina. It should be used in combination with amlodipine, beta-blockers or nitrates.
Nalfon
Pharmacology
Ranolazine has antianginal and anti-ischemic effects that do not depend upon reductions in heart rate or blood pressure. It is the first new anti-anginal developed in over 20 years.
Nalfon
Absorption
Absorption is highly variable. After oral administration of ranolazine as a solution, 73% of the dose is systemically available as ranolazine or metabolites. The bioavailability of oral ranolazine relative to that from a solution is 76%.
Nalfon
side effects and Toxicity
In the event of overdose, the expected symptoms would be dizziness, nausea/vomiting, diplopia, paresthesia, and confusion. Syncope with prolonged loss of consciousness may develop.
Nalfon
Patient Information
AMITIZA™ may cause nausea. If this occurs, concomitant administration of food with AMITIZA™ may reduce symptoms of nausea. AMITIZA™ should not be administered to patients that have severe diarrhea. Patients should be aware of the possible occurrence of diarrhea during treatment. If the diarrhea becomes severe consult your physician.
Nalfon
Organisms Affected
Humans and other mammals