Naftifine HCl
Brand names,
Naftifine HCl
Analogs
Naftifine HCl
Brand Names Mixture
Naftifine HCl
Chemical_Formula
C14H12O2
Naftifine HCl
RX_link
No information avaliable
Naftifine HCl
fda sheet
Naftifine HCl
msds (material safety sheet)
Naftifine HCl
Synthesis Reference
No information avaliable
Naftifine HCl
Molecular Weight
212.244 g/mol
Naftifine HCl
Melting Point
21 oC (boiling point 323-324 oC)
Naftifine HCl
H2O Solubility
15.4 mg/L
Naftifine HCl
State
Liquid
Naftifine HCl
LogP
3.599
Naftifine HCl
Dosage Forms
Gel; Lotion; Solution
Naftifine HCl
Indication
Used to kill lice and the mites responsible for the skin condition scabies.
Naftifine HCl
Pharmacology
Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. It is also used to treat lice infestation of the head and body. Benzyl benzoate is not the treatment of choice for scabies due to its irritant properties.
Naftifine HCl
Absorption
No data are available on percutaneous absorption of benzyl benzoate. Some older studies have suggested some percutaneous absorption, however the amount was not quantified.
Naftifine HCl
side effects and Toxicity
Oral, rabbit: LD50 = 1680 mg/kg; Skin, rabbit: LD50 = 4000 mg/kg. Symptoms of overdose include blister formation, crusting, itching, oozing, reddening, or scaling of skin; difficulty in urinating (dribbling); jerking movements; sudden loss of consciousness.
Naftifine HCl
Patient Information
Naftifine HCl
Organisms Affected
Sarcoptes scabiei