Naftin
Brand names,
Naftin
Analogs
Naftin
Brand Names Mixture
Naftin
Chemical_Formula
C14H12O2
Naftin
RX_link
No information avaliable
Naftin
fda sheet
Naftin
msds (material safety sheet)
Naftin
Synthesis Reference
No information avaliable
Naftin
Molecular Weight
212.244 g/mol
Naftin
Melting Point
21 oC (boiling point 323-324 oC)
Naftin
H2O Solubility
15.4 mg/L
Naftin
State
Liquid
Naftin
LogP
3.599
Naftin
Dosage Forms
Gel; Lotion; Solution
Naftin
Indication
Used to kill lice and the mites responsible for the skin condition scabies.
Naftin
Pharmacology
Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. It is also used to treat lice infestation of the head and body. Benzyl benzoate is not the treatment of choice for scabies due to its irritant properties.
Naftin
Absorption
No data are available on percutaneous absorption of benzyl benzoate. Some older studies have suggested some percutaneous absorption, however the amount was not quantified.
Naftin
side effects and Toxicity
Oral, rabbit: LD50 = 1680 mg/kg; Skin, rabbit: LD50 = 4000 mg/kg. Symptoms of overdose include blister formation, crusting, itching, oozing, reddening, or scaling of skin; difficulty in urinating (dribbling); jerking movements; sudden loss of consciousness.
Naftin
Patient Information
Naftin
Organisms Affected
Sarcoptes scabiei