Nabumetone en es it fr

Nabumetone Brand names, Nabumetone Analogs

Nabumetone Brand Names Mixture

  • No information avaliable

Nabumetone Chemical_Formula


Nabumetone RX_link

Nabumetone fda sheet

Nabumetone FDA

Nabumetone msds (material safety sheet)

Nabumetone MSDS

Nabumetone Synthesis Reference

No information avaliable

Nabumetone Molecular Weight

228.286 g/mol

Nabumetone Melting Point

No information avaliable

Nabumetone H2O Solubility

Practically insoluble

Nabumetone State


Nabumetone LogP


Nabumetone Dosage Forms

Tablets for oral administration (500 mg or 750 mg)

Nabumetone Indication

For acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.

Nabumetone Pharmacology

Nabumetone is a naphthylalkanone. It is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic and antipyretic properties in pharmacologic studies. As with other nonsteroidal anti-inflammatory agents, its mode of action is not known. However, the ability to inhibit prostaglandin synthesis may be involved in the anti-inflammatory effect.

Nabumetone Absorption

Well absorbed from the gastrointestinal tract. Coadministration of food increases the rate of absorption and subsequent appearance of 6MNA (the active metabolite) in the plasma but does not affect the extent of conversion of nabumetone into 6MNA.

Nabumetone side effects and Toxicity

The one overdose occurred in a 17-year-old female patient who had a history of abdominal pain and was hospitalized for increased abdominal pain following ingestion of 30 nabumetone tablets (15 grams total). Stools were negative for occult blood and there was no fall in serum hemoglobin concentration. The patient had no other symptoms.

Nabumetone Patient Information

Nabumetone Organisms Affected

Humans and other mammals