Mivacron
Mivacron Brand names, Mivacron Analogs
Mivacron Brand Names Mixture
- No information avaliable
Mivacron Chemical_Formula
C15H16O2
Mivacron RX_link
http://www.rxlist.com/cgi/generic/nabume.htm
Mivacron fda sheet
Mivacron msds (material safety sheet)
Mivacron Synthesis Reference
No information avaliable
Mivacron Molecular Weight
228.286 g/mol
Mivacron Melting Point
No information avaliable
Mivacron H2O Solubility
Practically insoluble
Mivacron State
Solid
Mivacron LogP
3.274
Mivacron Dosage Forms
Tablets for oral administration (500 mg or 750 mg)
Mivacron Indication
For acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Mivacron Pharmacology
Nabumetone is a naphthylalkanone. It is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic and antipyretic properties in pharmacologic studies. As with other nonsteroidal anti-inflammatory agents, its mode of action is not known. However, the ability to inhibit prostaglandin synthesis may be involved in the anti-inflammatory effect.
Mivacron Absorption
Well absorbed from the gastrointestinal tract. Coadministration of food increases the rate of absorption and subsequent appearance of 6MNA (the active metabolite) in the plasma but does not affect the extent of conversion of nabumetone into 6MNA.
Mivacron side effects and Toxicity
The one overdose occurred in a 17-year-old female patient who had a history of abdominal pain and was hospitalized for increased abdominal pain following ingestion of 30 nabumetone tablets (15 grams total). Stools were negative for occult blood and there was no fall in serum hemoglobin concentration. The patient had no other symptoms.
Mivacron Patient Information
Mivacron Organisms Affected
Humans and other mammals
