Muromonab
Muromonab Brand names, Muromonab Analogs
Muromonab Brand Names Mixture
- No information avaliable
Muromonab Chemical_Formula
C6460H9946N1720O2043S56
Muromonab RX_link
No information avaliable
Muromonab fda sheet
Muromonab msds (material safety sheet)
Muromonab Synthesis Reference
No information avaliable
Muromonab Molecular Weight
146189.7
Muromonab Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Muromonab H2O Solubility
No information avaliable
Muromonab State
Liquid
Muromonab LogP
-0.513
Muromonab Dosage Forms
Solution (IV injection)
Muromonab Indication
For treatment of organ transplant recipients, prevention of organ rejection
Muromonab Pharmacology
Used in organ transplant prophylaxis, Muromonab or OKT-3 binds specifically to the CD-3 complex, which is involved in antigen recognition and cell stimulation, on the surface of T lymphocytes. Immediately after administration CD-3-positive T lymphocytes are abruptly removed from circulation. It has been effective in reversing corticosteroid-resistant acute rejection in renal, liver, and cardiac transplant recipients.
Muromonab Absorption
No information avaliable
Muromonab side effects and Toxicity
No information avaliable
Muromonab Patient Information
No information avaliable
Muromonab Organisms Affected
Humans and other mammals
