Moxifloxacin hydrochloride en es it fr

Moxifloxacin hydrochloride Brand names, Moxifloxacin hydrochloride Analogs

Moxifloxacin hydrochloride Brand Names Mixture

  • No information avaliable

Moxifloxacin hydrochloride Chemical_Formula


Moxifloxacin hydrochloride RX_link

Moxifloxacin hydrochloride fda sheet

Moxifloxacin_hydrochloride FDA

Moxifloxacin hydrochloride msds (material safety sheet)

Moxifloxacin_hydrochloride MSDS

Moxifloxacin hydrochloride Synthesis Reference

No information avaliable

Moxifloxacin hydrochloride Molecular Weight

401.431 g/mol

Moxifloxacin hydrochloride Melting Point

238-242 oC

Moxifloxacin hydrochloride H2O Solubility

No information avaliable

Moxifloxacin hydrochloride State


Moxifloxacin hydrochloride LogP


Moxifloxacin hydrochloride Dosage Forms

Solution (250 mL bags containing 400 mg of drug); Tablets (400 mg)

Moxifloxacin hydrochloride Indication

For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).

Moxifloxacin hydrochloride Pharmacology

Moxifloxacin is a quinolone/fluoroquinolone antibiotic. Moxifloxacin can be used to treat infections caused by the following bacteria: Aerobic Gram-positive microorganisms: Corynebacterium species, Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus warneri, Streptococcus pneumoniae, and Streptococcus viridans group. Aerobic Gram-negative microorganisms: Acinetobacter lwoffii, Haemophilus influenzae, and Haemophilus parainfluenzae. Other microorganisms: Chlamydia trachomatis.
Moxifloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Notably the drug has 100 times higher affinity for bacterial DNA gyrase than for mammalian. Moxifloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.

Moxifloxacin hydrochloride Absorption

Well absorbed from the gastrointestinal tract. Absolute oral bioavailability is approximately 90%. Food has little effect on absorption.

Moxifloxacin hydrochloride side effects and Toxicity

Symptoms of overdose include CNS and gastrointestinal effects such as decreased activity, somnolence, tremor, convulsions, vomiting, and diarrhea. The minimal lethal intravenous dose in mice and rats is 100 mg/kg.

Moxifloxacin hydrochloride Patient Information

Avoid contaminating the applicator tip with material from the eye, fingers or other source. Systemically administered quinolones including moxifloxacin have been associated with hypersensitivity reactions, even following a single dose. Discontinue use immediately and contact your physician at the first sign of a rash or allergic reaction.

Moxifloxacin hydrochloride Organisms Affected

Enteric bacteria and other eubacteria