Mivacurium
Brand names,
Mivacurium
Analogs
Mivacurium
Brand Names Mixture
Mivacurium
Chemical_Formula
C58H80N2O14+2
Mivacurium
RX_link
http://www.rxlist.com/cgi/generic3/mivacur.htm
Mivacurium
fda sheet
Mivacurium
msds (material safety sheet)
Mivacurium
Synthesis Reference
No information avaliable
Mivacurium
Molecular Weight
1029.26 g/mol
Mivacurium
Melting Point
No information avaliable
Mivacurium
H2O Solubility
No information avaliable
Mivacurium
State
Liquid
Mivacurium
LogP
No information avaliable
Mivacurium
Dosage Forms
Solution (sterile, non-pyrogenic, with pH 3.5 to 5.0 containing mivacurium chloride equivalent to 2 mg/mL mivacurium in water for injection)
Mivacurium
Indication
For inpatients and outpatients, as an adjunct to general anesthesia, to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Mivacurium
Pharmacology
Mivacurium is a short-acting, nondepolarizing skeletal neuromuscular blocking agent which is hydrolyzed by plasma cholinesterase. Mivacurium results in a blockade of neuromuscular transmission by binding competitively with cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine. The neuromuscular block produced by mivacurium is readily antagonized by anticholinesterase agents. The deeper the level of neuromuscular block at reversal, the longer the time required for recovery of neuromuscular function and the greater the dose of anticholinesterase agent required. Because spontaneous recovery after mivacurium is rapid, routine reversal may not always result in a clinical benefit.
Mivacurium
Absorption
No information avaliable
Mivacurium
side effects and Toxicity
Overdosage with neuromuscular blocking agents may result in neuromuscular block beyond the time needed for surgery and anesthesia.
Mivacurium
Patient Information
Mivacurium
Organisms Affected
Humans and other mammals