Mycamine
Brand names,
Mycamine
Analogs
Mycamine
Brand Names Mixture
Mycamine
Chemical_Formula
C58H80N2O14+2
Mycamine
RX_link
http://www.rxlist.com/cgi/generic3/mivacur.htm
Mycamine
fda sheet
Mycamine
msds (material safety sheet)
Mycamine
Synthesis Reference
No information avaliable
Mycamine
Molecular Weight
1029.26 g/mol
Mycamine
Melting Point
No information avaliable
Mycamine
H2O Solubility
No information avaliable
Mycamine
State
Liquid
Mycamine
LogP
No information avaliable
Mycamine
Dosage Forms
Solution (sterile, non-pyrogenic, with pH 3.5 to 5.0 containing mivacurium chloride equivalent to 2 mg/mL mivacurium in water for injection)
Mycamine
Indication
For inpatients and outpatients, as an adjunct to general anesthesia, to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Mycamine
Pharmacology
Mivacurium is a short-acting, nondepolarizing skeletal neuromuscular blocking agent which is hydrolyzed by plasma cholinesterase. Mivacurium results in a blockade of neuromuscular transmission by binding competitively with cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine. The neuromuscular block produced by mivacurium is readily antagonized by anticholinesterase agents. The deeper the level of neuromuscular block at reversal, the longer the time required for recovery of neuromuscular function and the greater the dose of anticholinesterase agent required. Because spontaneous recovery after mivacurium is rapid, routine reversal may not always result in a clinical benefit.
Mycamine
Absorption
No information avaliable
Mycamine
side effects and Toxicity
Overdosage with neuromuscular blocking agents may result in neuromuscular block beyond the time needed for surgery and anesthesia.
Mycamine
Patient Information
Mycamine
Organisms Affected
Humans and other mammals