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Milaxen Brand names, Milaxen Analogs

Milaxen Brand Names Mixture

  • No information avaliable

Milaxen Chemical_Formula


Milaxen RX_link

No information avaliable

Milaxen fda sheet

Milaxen msds (material safety sheet)

Milaxen Synthesis Reference

No information avaliable

Milaxen Molecular Weight

662.54 g/mol

Milaxen Melting Point

153.5 oC

Milaxen H2O Solubility

No information avaliable

Milaxen State


Milaxen LogP


Milaxen Dosage Forms

Solution (injectable)

Milaxen Indication

Used as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations.

Milaxen Pharmacology

Hexafluorenium is a cholinesterase antagonist that can be used to prolong the relaxation effects of succinylcholine or suxamethonium chloride. Suxamethonium acts as a depolarizing muscle relaxant. It imitates the action of acetylcholine at the neuromuscular junction and is degraded by pseudocholinesterase, a plasma cholinesterase. The prolonged stimulation of the acetylcholine receptor results first in disorganized muscle contractions, then in profound relaxation. Cholinesterases catalyze the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid, a reaction necessary to allow a cholinergic neuron to return to its resting state after activation. There are two types of cholinesterase acetylcholinesterase and pseuodocholinesterase. The first hydrolyses acetylcholine more quickly; the latter hydrolyses butyrylcholine and succinylcholine more quickly. An absence or mutation of the pseudocholinesterase enzyme leads to a medical condition known simply as pseudocholinesterase deficiency. This is a silent condition that only manifests itself when people who have the deficiency receive the muscle relaxants succinylcholine or mivacurium during a surgery.

Milaxen Absorption

No information avaliable

Milaxen side effects and Toxicity

LD50 = 280 mg/kg (mouse, oral)

Milaxen Patient Information

No information avaliable

Milaxen Organisms Affected

Humans and other mammals