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Hexafluorenium Brand names, Hexafluorenium Analogs

Hexafluorenium Brand Names Mixture

  • No information avaliable

Hexafluorenium Chemical_Formula


Hexafluorenium RX_link

No information avaliable

Hexafluorenium fda sheet

Hexafluorenium msds (material safety sheet)

Hexafluorenium Synthesis Reference

No information avaliable

Hexafluorenium Molecular Weight

662.54 g/mol

Hexafluorenium Melting Point

153.5 oC

Hexafluorenium H2O Solubility

No information avaliable

Hexafluorenium State


Hexafluorenium LogP


Hexafluorenium Dosage Forms

Solution (injectable)

Hexafluorenium Indication

Used as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations.

Hexafluorenium Pharmacology

Hexafluorenium is a cholinesterase antagonist that can be used to prolong the relaxation effects of succinylcholine or suxamethonium chloride. Suxamethonium acts as a depolarizing muscle relaxant. It imitates the action of acetylcholine at the neuromuscular junction and is degraded by pseudocholinesterase, a plasma cholinesterase. The prolonged stimulation of the acetylcholine receptor results first in disorganized muscle contractions, then in profound relaxation. Cholinesterases catalyze the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid, a reaction necessary to allow a cholinergic neuron to return to its resting state after activation. There are two types of cholinesterase acetylcholinesterase and pseuodocholinesterase. The first hydrolyses acetylcholine more quickly; the latter hydrolyses butyrylcholine and succinylcholine more quickly. An absence or mutation of the pseudocholinesterase enzyme leads to a medical condition known simply as pseudocholinesterase deficiency. This is a silent condition that only manifests itself when people who have the deficiency receive the muscle relaxants succinylcholine or mivacurium during a surgery.

Hexafluorenium Absorption

No information avaliable

Hexafluorenium side effects and Toxicity

LD50 = 280 mg/kg (mouse, oral)

Hexafluorenium Patient Information

No information avaliable

Hexafluorenium Organisms Affected

Humans and other mammals