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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C11H15NO5
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RX_link
http://www.rxlist.com/cgi/generic/methocar.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
241.241 g/mol
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Melting Point
93 oC
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H2O Solubility
7200 mg/L
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State
Solid
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LogP
0.118
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Dosage Forms
Liquid (100 mg/mL in 10 mL vials); Tablet (500 mg and 750 mg) for oral administration
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Indication
For use as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions.
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Pharmacology
Methocarbamol is a central muscle relaxant for skeletal muscles, used to treat spasms. It is structurally related to guaifenesin. Methocarbamol's exact mechanism of causing skeletal muscle relaxation is unknown. It is thought to work centrally, perhaps by general depressant effects. It has no direct relaxant effects on striated muscle, nerve fibers, or the motor endplate. It will not directly relax contracted skeletal muscles. The drug has a secondary sedative effect.
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Absorption
Rapid. Onset of action is about 30 minutes after oral administration.
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side effects and Toxicity
Symptoms of overdose include blurred vision, coma, drowsiness, low blood pressure, nausea, and seizures.
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals