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Marplan Brand names, Marplan Analogs

Marplan Brand Names Mixture

  • No information avaliable

Marplan Chemical_Formula


Marplan RX_link

Marplan fda sheet

Marplan FDA

Marplan msds (material safety sheet)

Marplan Synthesis Reference

No information avaliable

Marplan Molecular Weight

231.251 g/mol

Marplan Melting Point

105-106 oC

Marplan H2O Solubility

1600 mg/L

Marplan State


Marplan LogP


Marplan Dosage Forms


Marplan Indication

Isocarboxazid is used to treat depression, especially when the patient is excitable or suffering from phobias (fears).

Marplan Pharmacology

Isocarboxazid is a non-selective hydrazine monoamine oxidase (MAO) inhibitor used to treat depression. In vivo and in vitro studies demonstrated inhibition of MAO in the brain, heart, and liver. Depression is a complicated disease that is not fully understood. It is thought that depression may be linked to an imbalance of chemicals within the brain. When depression occurs, there may be a decrease in the amount of chemicals released from nerve cells in the brain. These chemicals are called monoamines. Monoamines are broken down by a chemical called monoamine oxidase. Isocarboxazid prevents monoamine oxidase from breaking down the monoamines. This results in an increased amount of active monoamines in the brain. By increasing the amount of monoamines in the brain, the imbalance of chemicals thought to be caused by depression is altered. This helps relieve the symptoms of depression.

Marplan Absorption

Well absorbed from the gastrointestinal tract.

Marplan side effects and Toxicity

Signs of overdose include severe anxiety, confusion, convulsions, cool clammy skin, severe dizziness, severe drowsiness, fast and irregular pulse, fever, hallucinations, severe headache, high or low blood pressure, hyperactive reflexes, muscle stiffness, respiratory depression or failure, slowed reflexes, sweating, severe trouble in sleeping, and unusual irritability.

Marplan Patient Information

Marplan Organisms Affected

Humans and other mammals