Mannitol BP
Brand names,
Mannitol BP
Analogs
Mannitol BP
Brand Names Mixture
Mannitol BP
Chemical_Formula
C22H22O8
Mannitol BP
RX_link
http://www.rxlist.com/cgi/generic4/podophyllin.htm
Mannitol BP
fda sheet
Mannitol BP
msds (material safety sheet)
Mannitol BP
Synthesis Reference
No information avaliable
Mannitol BP
Molecular Weight
414.405 g/mol
Mannitol BP
Melting Point
228 oC
Mannitol BP
H2O Solubility
100 mg/L
Mannitol BP
State
Solid
Mannitol BP
LogP
2.229
Mannitol BP
Dosage Forms
No information avaliable
Mannitol BP
Indication
For treatment of external genital warts (Condyloma acuminatum).
Mannitol BP
Pharmacology
Podofilox, also called podophyllotoxin, is a purer and more stable form of podophyllin in which only the biologically active portion of the compound is present. Podofilox is used to remove certain types of warts on the outside skin of the genital areas.
Mannitol BP
Absorption
Topical application of 0.05 mL of 0.5% podofilox solution to external genitalia did not result in detectable serum levels. Applications of 0.1 to 1.5 mL resulted in peak serum levels of 1 to 17 ng/mL one to two hours after application.
Mannitol BP
side effects and Toxicity
No information avaliable
Mannitol BP
Patient Information
Mannitol BP
Organisms Affected
Condyloma acuminatum