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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C22H22O8
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RX_link
http://www.rxlist.com/cgi/generic4/podophyllin.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
414.405 g/mol
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Melting Point
228 oC
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H2O Solubility
100 mg/L
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State
Solid
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LogP
2.229
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Dosage Forms
No information avaliable
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Indication
For treatment of external genital warts (Condyloma acuminatum).
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Pharmacology
Podofilox, also called podophyllotoxin, is a purer and more stable form of podophyllin in which only the biologically active portion of the compound is present. Podofilox is used to remove certain types of warts on the outside skin of the genital areas.
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Absorption
Topical application of 0.05 mL of 0.5% podofilox solution to external genitalia did not result in detectable serum levels. Applications of 0.1 to 1.5 mL resulted in peak serum levels of 1 to 17 ng/mL one to two hours after application.
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side effects and Toxicity
No information avaliable
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Patient Information
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Organisms Affected
Condyloma acuminatum