Liothyronine
Brand names,
Liothyronine
Analogs
Liothyronine
Brand Names Mixture
Liothyronine
Chemical_Formula
C15H12I3NO4
Liothyronine
RX_link
http://www.rxlist.com/cgi/generic3/liothyronine.htm
Liothyronine
fda sheet
Liothyronine
msds (material safety sheet)
Liothyronine
Synthesis Reference
No information avaliable
Liothyronine
Molecular Weight
650.974 g/mol
Liothyronine
Melting Point
236.5 oC
Liothyronine
H2O Solubility
3.96 mg/L
Liothyronine
State
Solid
Liothyronine
LogP
3.001
Liothyronine
Dosage Forms
Tablet
Liothyronine
Indication
Used as replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyrodism during the recovery phase of subacute thyroiditis.
Liothyronine
Pharmacology
Thyroid hormone drugs are natural or synthetic preparations containing tetraiodothyronine (T4, levothyroxine) or triiodothyronine (T3, liothyronine) or both. T4 and T3 are produced in the human thyroid gland by the iodination and coupling of the amino acid tyrosine. Liothyronine (T3) contains three atoms of iodine and is formed by the coupling of one molecule of diiodotyrosine (DIT) with one molecule of monoiodotyrosine (MIT). These hormones enhance oxygen consumption by most tissues of the body and increase the basal metabolic rate and the metabolism of carbohydrates, lipids and proteins. Thus, they exert a profound influence on every organ system in the body and are of particular importance in the development of the central nervous system.
Liothyronine
Absorption
Almost totally absorbed, 95 percent in 4 hours.
Liothyronine
side effects and Toxicity
No information avaliable
Liothyronine
Patient Information
Liothyronine
Organisms Affected
Humans and other mammals