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Lescol Brand names, Lescol Analogs

Lescol Brand Names Mixture

  • No information avaliable

Lescol Chemical_Formula


Lescol RX_link


Lescol fda sheet

Lescol FDA

Lescol msds (material safety sheet)

Lescol Synthesis Reference

F. G. Kathawala, U.S. Pat. 4,739,073 (1988)

Lescol Molecular Weight

411.466 g/mol

Lescol Melting Point


Lescol H2O Solubility

0.46 mg/L

Lescol State


Lescol LogP


Lescol Dosage Forms

Capsules; Tablets (extended-release)

Lescol Indication

For management as an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels in patients with primary hypercholesterolemia and mixed dyslipidemia

Lescol Pharmacology

Fluvastatin, the first synthetically-prepared HMG-CoA reductase inhibitor, is used as an antilipemic to lower cholesterol and triglyceride levels associated with primary hypercholesterolemia and mixed dyslipidemia (Fredrickson types IIa and IIb) and to slow the progression of coronary atherosclerosis in patients with coronary artery disease. Although similar to lovastatin, simvastatin, and pravastatin, Fluvastatin has a shorter half-life, no active metabolites, extensive protein binding, and minimal CSF penetration.

Lescol Absorption

24% (range 9%-50%).

Lescol side effects and Toxicity

Variety of GI complaints and an increase in transaminase values (i.e., SGOT and SGPT).

Lescol Patient Information


Patients should be advised to report promptly unexplained muscle pain, tenderness or
weakness, particularly if accompanied by malaise or fever.

Women should be informed that if they become pregnant while receiving Lescol or Lescol
XL the drug should be discontinued immediately to avoid possible harmful effects on a
developing fetus from a relative deficit of cholesterol and biological products derived
from cholesterol. In addition, Lescol or Lescol XL should not be taken during nursing.

Lescol Organisms Affected

Humans and other mammals