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Brand names,
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Analogs
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Brand Names Mixture
- Anivy (Benzocaine + Chlorphenesin + Titanium Dioxide + Zinc Oxide)
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Chemical_Formula
C26H40O5
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RX_link
http://www.rxlist.com/cgi/generic/latanoprost.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
432.593 g/mol
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Melting Point
No information avaliable
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H2O Solubility
8 mg/mL
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State
Liquid
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LogP
4.027
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Dosage Forms
Solution
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Indication
For the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
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Pharmacology
Latanoprost is an isopropyl ester prodrug which is inactive but which becomes active after hydrolysis to the acid from. Latanoprost opthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes.
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Absorption
Latanoprost is well absorbed through the cornea where the isopropyl ester prodrug is hydrolyzed to the acid form. Peak concentration is reached 2 hrs after topical administration.
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side effects and Toxicity
Symptoms of overdose include bloodshot eyes and eye irritation.
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Patient Information
http://www.drugs.com/MTM/lactulose.html
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Organisms Affected
Humans and other mammals