Indecainide
Indecainide Brand names, Indecainide Analogs
Indecainide Brand Names Mixture
- No information avaliable
Indecainide Chemical_Formula
C20H24N2O
Indecainide RX_link
No information avaliable
Indecainide fda sheet
Indecainide msds (material safety sheet)
Indecainide Synthesis Reference
No information avaliable
Indecainide Molecular Weight
308.417 g/mol
Indecainide Melting Point
94-95 oC
Indecainide H2O Solubility
1.88 mg/L
Indecainide State
Solid
Indecainide LogP
4.535
Indecainide Dosage Forms
Extended release tablets (50, 75, 100 mg)
Indecainide Indication
For the treatment of life-threatening dysrhythmias and sustained ventricular tachycardia.
Indecainide Pharmacology
Indecainide is a rarely used antidysrhythmic. Indecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.
Indecainide Absorption
Nearly complete following oral administration.
Indecainide side effects and Toxicity
When given orally to either young adult rats or mice, the LD50 was 100 mg/kg. Symptoms of overdose include nausea and vomiting, convulsions, hypotension, bradycardia, syncope, extreme widening of the QRS complex, widening of the QT interval, widening of the PR interval, ventricular tachycardia, AV nodal block, asystole, bundle branch block, cardiac failure, and cardiac arrest.
Indecainide Patient Information
Indecainide Organisms Affected
Humans and other mammals
