Iloprost
Brand names,
Iloprost
Analogs
Iloprost
Brand Names Mixture
Iloprost
Chemical_Formula
C30H38O5
Iloprost
RX_link
http://www.rxlist.com/cgi/generic4/ventavis.htm
Iloprost
fda sheet
Iloprost
msds (material safety sheet)
Iloprost
Synthesis Reference
No information avaliable
Iloprost
Molecular Weight
478.62 g/mol
Iloprost
Melting Point
No information avaliable
Iloprost
H2O Solubility
Very slightly soluble
Iloprost
State
Solid
Iloprost
LogP
3.964
Iloprost
Dosage Forms
Solution; Aerosol delivery
Iloprost
Indication
Usednfor the treatment of pulmonary arterial hypertension.
Iloprost
Pharmacology
Iloprost is a synthetic analogue of prostacyclin PGI2. Iloprost dilates systemic and pulmonary arterial vascular beds. It also affects platelet aggregation but the relevance of this effect to the treatment of pulmonary hypertension is unknown. The two diastereoisomers of iloprost differ in their potency in dilating blood vessels, with the 4S isomer substantially more potent than the 4R isomer.
Iloprost
Absorption
Rapidly absorbed with bioavailability of 63%
Iloprost
side effects and Toxicity
Overdoses can lead to hypotension, headache, flushing, nausea, vomiting, and diarrhea.
Iloprost
Patient Information
Iloprost
Organisms Affected
Humans and other mammals