Ventavis
Brand names,
Ventavis
Analogs
Ventavis
Brand Names Mixture
Ventavis
Chemical_Formula
C30H38O5
Ventavis
RX_link
http://www.rxlist.com/cgi/generic4/ventavis.htm
Ventavis
fda sheet
Ventavis
msds (material safety sheet)
Ventavis
Synthesis Reference
No information avaliable
Ventavis
Molecular Weight
478.62 g/mol
Ventavis
Melting Point
No information avaliable
Ventavis
H2O Solubility
Very slightly soluble
Ventavis
State
Solid
Ventavis
LogP
3.964
Ventavis
Dosage Forms
Solution; Aerosol delivery
Ventavis
Indication
Usednfor the treatment of pulmonary arterial hypertension.
Ventavis
Pharmacology
Iloprost is a synthetic analogue of prostacyclin PGI2. Iloprost dilates systemic and pulmonary arterial vascular beds. It also affects platelet aggregation but the relevance of this effect to the treatment of pulmonary hypertension is unknown. The two diastereoisomers of iloprost differ in their potency in dilating blood vessels, with the 4S isomer substantially more potent than the 4R isomer.
Ventavis
Absorption
Rapidly absorbed with bioavailability of 63%
Ventavis
side effects and Toxicity
Overdoses can lead to hypotension, headache, flushing, nausea, vomiting, and diarrhea.
Ventavis
Patient Information
Ventavis
Organisms Affected
Humans and other mammals