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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C6382H9830N1672O1979S54
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RX_link
http://www.rxlist.com/cgi/generic3/zevalin.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
143375.5
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Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
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H2O Solubility
No information avaliable
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State
Liquid
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LogP
-0.359
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Dosage Forms
Solution (IV Infusion)
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Indication
For treatment of non-Hodgkin's lymphoma
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Pharmacology
Zevalin binds to the CD20 antigen, which is predominantly expressed on mature B cells and on >90% of B-cell non-Hodgkin's lympohomas. The antibody leads to selective killing of B-cells.
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Absorption
No information avaliable
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals