Hydroxocobalamin monohydrochloride
Hydroxocobalamin monohydrochloride Brand names, Hydroxocobalamin monohydrochloride Analogs
Hydroxocobalamin monohydrochloride Brand Names Mixture
- 2% Polocaine Dental with Levonordefrin 1:20,000 (Corbadrine + Mepivacaine Hydrochloride)
- Arestocaine Hcl 2% W Levonordefrin 1:20000 (Levonordefrin Hydrochloride + Mepivacaine Hydrochloride)
- Carbocaine 2% Neo-Cobefrin 1:20,000 Liq (Levonordefrin Hydrochloride + Mepivacaine Hydrochloride)
- Carbocaine 2% with Neo-Cobefrin (Corbadrine + Mepivacaine Hydrochloride)
- Isocaine Hcl Inj 2% (Levonordefrin Hydrochloride (Levonordefrin Hydrochloride) + Mepivacaine Hydrochloride)
- Mepivacaine Hcl 2% W Levonordefrin Inj (Levonordefrin Hydrochloride + Mepivacaine Hydrochloride)
- Scandonest 2% Special Inj (Epinephrine + Mepivacaine Hydrochloride)
Hydroxocobalamin monohydrochloride Chemical_Formula
C62H89CoN13O15P
Hydroxocobalamin monohydrochloride RX_link
http://www.rxlist.com/drugs/drug-60358-Alpha-Redisol+Intramuscular.aspx?drugid=60358&drugname=Alpha-Redisol+Intramuscular
Hydroxocobalamin monohydrochloride fda sheet
Hydroxocobalamin monohydrochloride msds (material safety sheet)
Hydroxocobalamin monohydrochloride Synthesis Reference
No information avaliable
Hydroxocobalamin monohydrochloride Molecular Weight
1345.5663 g/mol
Hydroxocobalamin monohydrochloride Melting Point
No information avaliable
Hydroxocobalamin monohydrochloride H2O Solubility
No information avaliable
Hydroxocobalamin monohydrochloride State
Solid
Hydroxocobalamin monohydrochloride LogP
No information avaliable
Hydroxocobalamin monohydrochloride Dosage Forms
Tablet; Liquid; Solution
Hydroxocobalamin monohydrochloride Indication
For treatment of pernicious anemia and the prevention and treatment of vitamin B12 deficiency arising from alcoholism, malabsorption, tapeworm infestation, celiac, hyperthyroidism, hepatic-biliary tract disease, persistent diarrhea, ileal resection, pancreatic cancer, renal disease, prolonged stress, vegan diets, macrobiotic diets or other restrictive diets. Also used as a cyanide poisoning antidote
Hydroxocobalamin monohydrochloride Pharmacology
Hydroxocobalamin is a synthetic, injectable form of Vitamin B 12. Hydroxocobalamin is actually a precursor of two cofactors or vitamins (Vitamin B12 and Methylcobalamin) which are involved in various biological systems in man. Vitamin B12 is required for the conversion of methylmalonate to succinate. Deficiency of this enzyme could therefore interfere with the production of lipoprotein in myelin sheath tissue and so give rise to neurological lesions. The second cofactor, Methylcobalamin, is necessary for the conversion of homocysteine to methionine which is essential for the metabolism of folic acid. Deficiency of tetrahydrafolate leads to reduced synthesis of thymidylate resulting in reduced synthesis of DNA which is essential for cell maturation. Vitamin B12 is also concerned in the maintenance of sulphydryl groups in reduced form, deficiency leading to decreased amounts of reduced SH content of erythrocytes and liver cells. Overall, vitamin B12 acts as a coenzyme for various metabolic functions, including fat and carbohydrate metabolism and protein synthesis. It is necessary for growth, cell replication, hematopoiesis, and nucleoprotein as well as myelin synthesis. This is largely due to its effects on metabolism of methionine folic acid, and malonic acid
Hydroxocobalamin monohydrochloride Absorption
Readily absorbed from the gastrointestinal tract, except in malabsorption syndromes. Vitamin B12 is absorbed in the lower half of the ileum.
Hydroxocobalamin monohydrochloride side effects and Toxicity
No information avaliable
Hydroxocobalamin monohydrochloride Patient Information
http://www.drugs.com/pdr/HYDROMORPHONE_HYDROCHLORIDE.html
Hydroxocobalamin monohydrochloride Organisms Affected
Humans and other mammals
