Hydroxocobalamin acetate
Hydroxocobalamin acetate Brand names, Hydroxocobalamin acetate Analogs
Hydroxocobalamin acetate Brand Names Mixture
- 2% Polocaine Dental with Levonordefrin 1:20,000 (Corbadrine + Mepivacaine Hydrochloride)
- Arestocaine Hcl 2% W Levonordefrin 1:20000 (Levonordefrin Hydrochloride + Mepivacaine Hydrochloride)
- Carbocaine 2% Neo-Cobefrin 1:20,000 Liq (Levonordefrin Hydrochloride + Mepivacaine Hydrochloride)
- Carbocaine 2% with Neo-Cobefrin (Corbadrine + Mepivacaine Hydrochloride)
- Isocaine Hcl Inj 2% (Levonordefrin Hydrochloride (Levonordefrin Hydrochloride) + Mepivacaine Hydrochloride)
- Mepivacaine Hcl 2% W Levonordefrin Inj (Levonordefrin Hydrochloride + Mepivacaine Hydrochloride)
- Scandonest 2% Special Inj (Epinephrine + Mepivacaine Hydrochloride)
Hydroxocobalamin acetate Chemical_Formula
C62H89CoN13O15P
Hydroxocobalamin acetate RX_link
http://www.rxlist.com/drugs/drug-60358-Alpha-Redisol+Intramuscular.aspx?drugid=60358&drugname=Alpha-Redisol+Intramuscular
Hydroxocobalamin acetate fda sheet
Hydroxocobalamin acetate msds (material safety sheet)
Hydroxocobalamin acetate Synthesis Reference
No information avaliable
Hydroxocobalamin acetate Molecular Weight
1345.5663 g/mol
Hydroxocobalamin acetate Melting Point
No information avaliable
Hydroxocobalamin acetate H2O Solubility
No information avaliable
Hydroxocobalamin acetate State
Solid
Hydroxocobalamin acetate LogP
No information avaliable
Hydroxocobalamin acetate Dosage Forms
Tablet; Liquid; Solution
Hydroxocobalamin acetate Indication
For treatment of pernicious anemia and the prevention and treatment of vitamin B12 deficiency arising from alcoholism, malabsorption, tapeworm infestation, celiac, hyperthyroidism, hepatic-biliary tract disease, persistent diarrhea, ileal resection, pancreatic cancer, renal disease, prolonged stress, vegan diets, macrobiotic diets or other restrictive diets. Also used as a cyanide poisoning antidote
Hydroxocobalamin acetate Pharmacology
Hydroxocobalamin is a synthetic, injectable form of Vitamin B 12. Hydroxocobalamin is actually a precursor of two cofactors or vitamins (Vitamin B12 and Methylcobalamin) which are involved in various biological systems in man. Vitamin B12 is required for the conversion of methylmalonate to succinate. Deficiency of this enzyme could therefore interfere with the production of lipoprotein in myelin sheath tissue and so give rise to neurological lesions. The second cofactor, Methylcobalamin, is necessary for the conversion of homocysteine to methionine which is essential for the metabolism of folic acid. Deficiency of tetrahydrafolate leads to reduced synthesis of thymidylate resulting in reduced synthesis of DNA which is essential for cell maturation. Vitamin B12 is also concerned in the maintenance of sulphydryl groups in reduced form, deficiency leading to decreased amounts of reduced SH content of erythrocytes and liver cells. Overall, vitamin B12 acts as a coenzyme for various metabolic functions, including fat and carbohydrate metabolism and protein synthesis. It is necessary for growth, cell replication, hematopoiesis, and nucleoprotein as well as myelin synthesis. This is largely due to its effects on metabolism of methionine folic acid, and malonic acid
Hydroxocobalamin acetate Absorption
Readily absorbed from the gastrointestinal tract, except in malabsorption syndromes. Vitamin B12 is absorbed in the lower half of the ileum.
Hydroxocobalamin acetate side effects and Toxicity
No information avaliable
Hydroxocobalamin acetate Patient Information
http://www.drugs.com/pdr/HYDROMORPHONE_HYDROCHLORIDE.html
Hydroxocobalamin acetate Organisms Affected
Humans and other mammals
