Ganirelix
Brand names,
Ganirelix
Analogs
Ganirelix
Brand Names Mixture
Ganirelix
Chemical_Formula
No information avaliable
Ganirelix
RX_link
http://www.rxlist.com/cgi/generic2/ganirelix.htm
Ganirelix
fda sheet
Ganirelix
msds (material safety sheet)
Ganirelix
Synthesis Reference
No information avaliable
Ganirelix
Molecular Weight
1570.4 g/mol
Ganirelix
Melting Point
No information avaliable
Ganirelix
H2O Solubility
No information avaliable
Ganirelix
State
Liquid
Ganirelix
LogP
No information avaliable
Ganirelix
Dosage Forms
Liquid; Solution
Ganirelix
Indication
Indicated for the inhibition of premature LH surges in women undergoing controlled ovarian hyperstimulation
Ganirelix
Pharmacology
Ganirelix is a GnRH antagonist, which modulates the hypothalamic-pituitary-gonadal axis by competitive binding to the GnRH receptors in the pituitary gland. As a result a rapid, profound, reversible suppression of endogenous gonadotrophins occurs, without initial stimulation as induced by GnRH agonists.
Ganirelix
Absorption
Rapidly absorbed following subcutaneous injection. The mean absolute bioavailability of Ganirelix following a single 250 µg subcutaneous injection to healthy female volunteers is 91.1%.
Ganirelix
side effects and Toxicity
No information avaliable
Ganirelix
Patient Information
No information avaliable
Ganirelix
Organisms Affected
Humans and other mammals