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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
No information avaliable
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RX_link
http://www.rxlist.com/cgi/generic2/ganirelix.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
1570.4 g/mol
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Melting Point
No information avaliable
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H2O Solubility
No information avaliable
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State
Liquid
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LogP
No information avaliable
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Dosage Forms
Liquid; Solution
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Indication
Indicated for the inhibition of premature LH surges in women undergoing controlled ovarian hyperstimulation
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Pharmacology
Ganirelix is a GnRH antagonist, which modulates the hypothalamic-pituitary-gonadal axis by competitive binding to the GnRH receptors in the pituitary gland. As a result a rapid, profound, reversible suppression of endogenous gonadotrophins occurs, without initial stimulation as induced by GnRH agonists.
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Absorption
Rapidly absorbed following subcutaneous injection. The mean absolute bioavailability of Ganirelix following a single 250 µg subcutaneous injection to healthy female volunteers is 91.1%.
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals