Ethiodol
Brand names,
Ethiodol
Analogs
Ethiodol
Brand Names Mixture
Ethiodol
Chemical_Formula
No information avaliable
Ethiodol
RX_link
http://www.rxlist.com/cgi/generic2/ethiodol.htm
Ethiodol
fda sheet
Ethiodol
msds (material safety sheet)
Ethiodol
Synthesis Reference
No information avaliable
Ethiodol
Molecular Weight
No information avaliable
Ethiodol
Melting Point
125oC (boiling point at 8mm Hg)
Ethiodol
H2O Solubility
Insoluble
Ethiodol
State
Liquid
Ethiodol
LogP
No information avaliable
Ethiodol
Dosage Forms
Liquid for injection (10mL ampules)
Ethiodol
Indication
For use as a radio-opaque medium for hysterosalpingography and lymphography, and as an antineoplastic agent when part of the iodine is 131-I.
Ethiodol
Pharmacology
There has been little detailed investigation of the metabolic fate of ethiodol in either man or animals. However, the fate of ethiodol following Iymphangiography in dogs has been reported. Koehler et al. employed I131-tagged ethiodol for lymphangiography in dogs and analyses of individual organs at various time intervals were done. The investigators reported an average of only 25% of the injected medium was retained in the lymphatics at the end of three days. An average of 50% was recovered from the lungs. They found the remainder of injected activity was fairly uniformly distributed throughout the body. Urinary excretion in the form of inorganic iodine was revealed as the chief mode of iodine loss from the system.
Ethiodol
Absorption
No information avaliable
Ethiodol
side effects and Toxicity
Intravenous LD50 in dog is 1580mg/kg. Symptoms of overdose include dyspnea and change in clotting factors.
Ethiodol
Patient Information
No information avaliable
Ethiodol
Organisms Affected
Humans and other mammals