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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
No information avaliable
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RX_link
http://www.rxlist.com/cgi/generic2/ethiodol.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
No information avaliable
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Melting Point
125oC (boiling point at 8mm Hg)
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H2O Solubility
Insoluble
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State
Liquid
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LogP
No information avaliable
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Dosage Forms
Liquid for injection (10mL ampules)
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Indication
For use as a radio-opaque medium for hysterosalpingography and lymphography, and as an antineoplastic agent when part of the iodine is 131-I.
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Pharmacology
There has been little detailed investigation of the metabolic fate of ethiodol in either man or animals. However, the fate of ethiodol following Iymphangiography in dogs has been reported. Koehler et al. employed I131-tagged ethiodol for lymphangiography in dogs and analyses of individual organs at various time intervals were done. The investigators reported an average of only 25% of the injected medium was retained in the lymphatics at the end of three days. An average of 50% was recovered from the lungs. They found the remainder of injected activity was fairly uniformly distributed throughout the body. Urinary excretion in the form of inorganic iodine was revealed as the chief mode of iodine loss from the system.
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Absorption
No information avaliable
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side effects and Toxicity
Intravenous LD50 in dog is 1580mg/kg. Symptoms of overdose include dyspnea and change in clotting factors.
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals