Ethambutol
Ethambutol Brand names, Ethambutol Analogs
Ethambutol Brand Names Mixture
- No information avaliable
Ethambutol Chemical_Formula
C10H24N2O2
Ethambutol RX_link
http://www.rxlist.com/cgi/generic2/ethambutol.htm
Ethambutol fda sheet
Ethambutol msds (material safety sheet)
Ethambutol Synthesis Reference
No information avaliable
Ethambutol Molecular Weight
204.31 g/mol
Ethambutol Melting Point
88 oC
Ethambutol H2O Solubility
No information avaliable
Ethambutol State
Solid
Ethambutol LogP
-0.14
Ethambutol Dosage Forms
Tablet (100, 400 mg)
Ethambutol Indication
For use, as an adjunct, in the treatment of pulmonary tuberculosis.
Ethambutol Pharmacology
Ethambutol is an oral chemotherapeutic agent which is specifically effective against actively growing microorganisms of the genus Mycobacterium, including M. tuberculosis. Ethambutol inhibits RNA synthesis and decreases tubercle bacilli replication. Nearly all strains of M. tuberculosis and M. kansasii as well as a number of strains of MAC are sensitive to ethambutol.
Ethambutol Absorption
About 75% to 80% of an orally administered dose of ethambutol is absorbed from the gastrointestinal tract.
Ethambutol side effects and Toxicity
The most commonly recognized toxic effect of ethambutol is optic neuropathy, which generally is considered uncommon and reversible in medical literature. Other side effects that have been observed are pruritus, joint pain, gastrointestinal upset, abdominal pain, malaise, headache, dizziness, mental confusion, disorientation, and possible hallucinations.
Ethambutol Patient Information
Ethambutol Organisms Affected
Humans and other mammals
