Ertapenem
Brand names,
Ertapenem
Analogs
Ertapenem
Brand Names Mixture
Ertapenem
Chemical_Formula
C22H25N3O7S
Ertapenem
RX_link
http://www.rxlist.com/cgi/generic3/invanz.htm
Ertapenem
fda sheet
Ertapenem
msds (material safety sheet)
Ertapenem
Synthesis Reference
No information avaliable
Ertapenem
Molecular Weight
475.516 g/mol
Ertapenem
Melting Point
No information avaliable
Ertapenem
H2O Solubility
Soluble as sodium salt
Ertapenem
State
Solid
Ertapenem
LogP
0.712
Ertapenem
Dosage Forms
Powder for solution
Ertapenem
Indication
For the treatment the following moderate to severe infections caused by susceptible isolates of the designated microorganisms: (1) complicated intra-abdominal infections due to Escherichia coli, Clostridium clostridioforme, Eubacterium lentum, Peptostreptococcus species, Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, or Bacteroides uniformis, (2) complicated skin and skin structure infections, including diabetic foot infections without osteomyelitis due to Staphylococcus aureus (methicillin susceptible isolates only), Streptococcus agalactiae, Streptococcus pyogenes, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Bacteroides fragilis, Peptostreptococcus species, Porphyromonas asaccharolytica, or Prevotella bivia, (3) community acquired pneumonia due to Streptococcus pneumoniae (penicillin susceptible isolates only) including cases with concurrent bacteremia, Haemophilus influenzae (beta-lactamase negative isolates only), or Moraxella catarrhalis, (4) complicated urinary tract infections including pyelonephritis due to Escherichia coli, including cases with concurrent bacteremia, or Klebsiella pneumoniae, (5) acute pelvic infections including postpartum endomyometritis, septic abortion and post surgical gynecologic infections due to Streptococcus agalactiae, Escherichia coli, Bacteroides fragilis, Porphyromonas asaccharolytica, Peptostreptococcus species, or Prevotella bivia.
Ertapenem
Pharmacology
Ertapenem has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria.
Ertapenem
Absorption
The mean bioavailability is approximately 90%.
Ertapenem
side effects and Toxicity
No information avaliable
Ertapenem
Patient Information
Ertapenem
Organisms Affected
Enteric bacteria and other eubacteria