Penetrex
Brand names,
Penetrex
Analogs
Penetrex
Brand Names Mixture
Penetrex
Chemical_Formula
C22H25N3O7S
Penetrex
RX_link
http://www.rxlist.com/cgi/generic3/invanz.htm
Penetrex
fda sheet
Penetrex
msds (material safety sheet)
Penetrex
Synthesis Reference
No information avaliable
Penetrex
Molecular Weight
475.516 g/mol
Penetrex
Melting Point
No information avaliable
Penetrex
H2O Solubility
Soluble as sodium salt
Penetrex
State
Solid
Penetrex
LogP
0.712
Penetrex
Dosage Forms
Powder for solution
Penetrex
Indication
For the treatment the following moderate to severe infections caused by susceptible isolates of the designated microorganisms: (1) complicated intra-abdominal infections due to Escherichia coli, Clostridium clostridioforme, Eubacterium lentum, Peptostreptococcus species, Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, or Bacteroides uniformis, (2) complicated skin and skin structure infections, including diabetic foot infections without osteomyelitis due to Staphylococcus aureus (methicillin susceptible isolates only), Streptococcus agalactiae, Streptococcus pyogenes, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Bacteroides fragilis, Peptostreptococcus species, Porphyromonas asaccharolytica, or Prevotella bivia, (3) community acquired pneumonia due to Streptococcus pneumoniae (penicillin susceptible isolates only) including cases with concurrent bacteremia, Haemophilus influenzae (beta-lactamase negative isolates only), or Moraxella catarrhalis, (4) complicated urinary tract infections including pyelonephritis due to Escherichia coli, including cases with concurrent bacteremia, or Klebsiella pneumoniae, (5) acute pelvic infections including postpartum endomyometritis, septic abortion and post surgical gynecologic infections due to Streptococcus agalactiae, Escherichia coli, Bacteroides fragilis, Porphyromonas asaccharolytica, Peptostreptococcus species, or Prevotella bivia.
Penetrex
Pharmacology
Ertapenem has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria.
Penetrex
Absorption
The mean bioavailability is approximately 90%.
Penetrex
side effects and Toxicity
No information avaliable
Penetrex
Patient Information
Penetrex
Organisms Affected
Enteric bacteria and other eubacteria