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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C16H14N2O4
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
298.293 g/mol
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Melting Point
No information avaliable
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H2O Solubility
No information avaliable
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State
Solid
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LogP
3.26
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Dosage Forms
Oral paste (5%, 5g)
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Indication
Used as a paste in the mouth to treat aphthous ulcers (canker sores).
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Pharmacology
Amlexanox is a mucoadhesive oral paste which has been clinically proven to abort the onset, accelerate healing and resolve the pain of aphthous ulcers (canker sores). It decreases the time ulcers take to heal. Because amlexanox decreases the healing time, it also decreases the pain you feel. Recent studies have also shown that the majority of ulcers can be prevented by application of the paste during the prodromal (pre-ulcerative) phase of the disease. Recurrent Aphthous Ulcers (RAU) also known as Recurrent Aphthous Stomatitis (RAS) is recognized as the most common oral mucosal disease known to man. Estimates suggest that 20% - 25% of the general population suffer at least one incidence of aphthous ulcers each year.
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Absorption
No significant absorption directly through the active ulcer. Most of the systemic absorption is via the gastrointestinal tract.
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side effects and Toxicity
No information avaliable
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Patient Information
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Organisms Affected
Humans and other mammals